Zuprevo 18% by Merck
RX Required
Zuprevo 18% by Merck
Zuprevo 18% contains tildipirosin, a macrolide antibiotic. For treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni, and for control of respiratory disease in cattle at high risk of developing BRD associated with M. haemolytica, P. multocida and H. somni. For use in beef and non-lactating dairy cattle. Each ml of Zuprevo contains 180 mg tildipirosin. A single dose of Zuprevo concentrates in the lungs for 28 days and in bronchial fluid for 21 days to treat and control BRD. Administer one dose, 1 ml per 100 lbs. SQ in the neck, not to exceed 10 ml per injection site. Zuprevo is not for use in female dairy cattle 20 months of age or older, or in calves to be processed for veal. 180 mg/ml Tildipirosin.
Important Safety Information:
Directions:
Inject subcutaneously as a single dose in the neck at a dosage of 4 mg/kg (1 mL/100 lb) body weight (BW). Do not inject more than 10 mL per injection site. Do not puncture the stopper of the respective vial size more than the tested number of punctures, shown in Table 1.
Clinical field studies indicate that administration of Zuprevo 18% (tildipirosin) Injectable Solution is effective for the control of respiratory disease in beef and non-lactating dairy cattle at “high risk” of developing BRD. Calves at high risk of developing BRD typically experience one or more of the following risk factors:
- Commingling from multiple sale barns/sources
- Extended transport times and shrink
- Exposure to wet or cold weather conditions or wide temperature swings
- Stressful arrival processing procedures (such as castration, dehorning, or branding)
- Recent weaning and poor vaccination history
Warnings:
For use in animals only. Not for human use. Keep out of reach of children. To avoid accidental injection, do not use in automatically powered syringes which have no additional protection system. In case of human injection, seek medical advice immediately and show the package insert or label to the physician.
RESIDUE WARNING:
Cattle intended for human consumption must not be slaughtered within 21 days of the last treatment. Do not use in female dairy cattle 20 months of age or older. Use of this drug product in these cattle may cause milk residue. A withdrawal period has not been established in pre-ruminating calves. Do not use in calves to be processed for veal.
Precautions:
The effects of Zuprevo 18% on bovine reproductive performance, pregnancy and lactation have not been determined. Swelling and inflammation, which may be severe, may be seen at the injection site after administration. Subcutaneous injection may result in local tissue reactions which persist beyond the slaughter withdrawal period. This may result in trim loss of edible tissue at slaughter.
DO NOT USE ZUPREVO 18% IN SWINE. Fatal adverse events have been reported following the use of tildipirosin in swine. NOT FOR USE IN CHICKENS OR TURKEYS.
Zuprevo 18% by Merck Highlights:
- Manufacturer: Merck Animal Health
- Low volume dosage means less injection site reactions and tissue damage
- Dosage One low-volume dose of 1 mL/100 lbs means less handling and more doses per bottle
- Rapid Absorption Rapidly absorbed after administration, reaching peak plasma levels in just 45 minutes
- Meat Withdrawal Time With 21 days meat withdrawal time there’s greater flexibility to make go-to-market decisions
- Long lasting product stays at treatment levels in the lungs for up to 28 days meaning less stress, lower treatment costs, and reduced labor
More Information
| SKU | Zuprevo_cp |
|---|---|
| Manufacturer | Merck Animal Health |
| Ailment | BRD |
| Hazardous | No |
| ORMD | No |
| Species | Calf, Cattle |
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