Arovyn Injectable Solution

AROVYN Injectable Solution is for use in beef cattle (including suckling calves), non-lactating dairy cattle (including dairy calves), veal calves, and swine. Not for use in female dairy cattle 20 months of age or older. AROVYN is a ready-to-use sterile parenteral preparation containing tulathromycin, a semi-synthetic macrolide antibiotic of the subclass triamilide. Each mL of AROVYN contains 100 mg of tulathromycin, 500 mg propylene glycol, 19.2 mg citric acid and 5 mg monothioglycerol. Sodium hydroxide or hydrochloric acid may be added to adjust pH. AROVYN consists of an equilibrated mixture of two isomeric forms of tulathromycin in a 9:1 ratio.

Arovyn Injectable Solution (tulathromycin injection) is a broad-spectrum antibiotic for beef cattle and calves, dairy cattle under 20 months of age and swine. Use in the treatment of major pathogens associated with bovine respiratory disease (BRD), foot rot and pinkeye. In beef and non-lactating dairy cattle, use to treat specific pathogens such as Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis associated with BRD. Treats pinkeye or infectious bovine keratoconjunctivitis (IBK) associated with Moraxella bovis, in addition to foot rot associated with Fusobacterium necrophorum and Porphyromonas levii. In suckling calves, dairy calves, and veal calves, use to treat BRD associated with M. haemolytica, P. multocida, H. somni, and M. bovis.

AROVYN Indications

Beef and Non-Lactating Dairy Cattle BRD – AROVYN Injectable Solution is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis; and for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis. IBK – AROVYN Injectable Solution is indicated for the treatment of infectious bovine keratoconjunctivitis (IBK) associated with Moraxella bovis. Foot Rot – AROVYN Injectable Solution is indicated for the treatment of bovine foot rot (interdigital necrobacillosis) associated with Fusobacterium necrophorum and Porphyromonas levii. Suckling Calves, Dairy Calves, and Veal Calves BRD - AROVYN Injectable Solution is indicated for the treatment of BRD associated with M. haemolytica, P. multocida, H. somni, and M. bovis. Swine AROVYN Injectable Solution is indicated for the treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica, Haemophilus parasuis, and Mycoplasma hyopneumoniae; and for the control of SRD associated with Actinobacillus pleuropneumoniae

AROVYN PreCautions

Cattle The effects of AROVYN on bovine reproductive performance, pregnancy, and lactation have not been determined. Subcutaneous injection can cause a transient local tissue reaction that may result in trim loss of edible tissue at slaughter. Swine The effects of AROVYN on porcine reproductive performance, pregnancy, and lactation have not been determined. Intramuscular injection can cause a transient local tissue reaction that may result in trim loss of edible tissue at slaughter

Storage Conditions

Store below 30°C (86°F), with excursions up to 40°C (104°F). Use this product within 84 days of the first puncture and puncture a maximum of 20 times. If more than 20 punctures are anticipated, the use of automatic injection equipment or a repeater syringe is recommended. When using a draw-off spike or needle with bore diameter larger than 16 gauge, discard any product remaining in the vial immediately after use.

Dosage and Administration

Cattle

Inject subcutaneously as a single dose in the neck at a dosage of 2.5 mg/kg (1.1 mL/100 lb) body weight (BW). Do not inject more than 10 mL per injection site.

Swine

Inject intramuscularly as a single dose in the neck at a dosage of 2.5 mg/kg (0.25 mL/22 lb) BW. Do not inject more than 2.5 mL per injection site.

Available Sizes of AROVYN

• 50 ML
• 100 ML
• 250 ML
• 500 ML

Arovyn Injectable Solution Highlights:

• SKU: arovyn_injectable_CP
• Manufacturer: Merck Animal Health
• For use in animals only
• Not for use in chickens or turkeys
• Cattle: 18-day slaughter withhold
• Swine: 5-day slaughter withhold
• FDA-approved for BRD, pinkeye and foot rot
• Each ml contains 100 mg of tulathromycin
• Not for human use. Keep out of reach of children
• Not for use in female dairy cattle 20 months of age or older
• Store below 30°C (86°F), with excursions up to 40°C (104°F)
• Broad-spectrum antibiotic to treat the major causes of BRD in cattle
• Broad-spectrum antibiotic to treat the major causes of SRD in swine
• Should not be used in animals known to be hypersensitive to the product
• Proficiently absorbs into the site of infection, in the lungs for quick response where it’s needed most
• Subcutaneous injection can cause a transient local tissue reaction, which may result in trim loss of edible tissue at slaughter in both cattle and swine
• This drug is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows