Zoetis Protivity [100 mL] (50 ds)

Protivity is a modified-live bacterial vaccine that is effective in protecting healthy beef and dairy calves against respiratory disease caused by Mycoplasma bovis (M. bovis). Calves 1 week of age or older can receive Protivity.

In a challenge study, Protivity vaccination generated 74% (p < 0.0001) reduction of total lung lesions (mean percentage), relative to controls.2 Calves at a young age are especially vulnerable to M. bovis infection. With a label indication that allows administration at 1 week of age, this allows for calves to receive two doses for protection against M. bovis by six weeks of age

Indications:

This product has been shown to be effective for the vaccination of healthy cattle 1 week of age or older against respiratory disease caused byMycoplasma bovis. Duration of immunity has not been established.

Protivity Doseage Information

• General Directions: Aseptically rehydrate the freeze-dried vaccine with the sterile diluent provided, mix well and administer 2 mL subcutaneously.
• Primary Vaccination: Healthy cattle should receive two doses administered 21 days apart.
• Revaccination: The need for annual booster vaccination has not been established for this product; consultation with a veterinarian or the manufacturer is recommended.

Safety Information:

A field safety study was conducted to demonstrate the safety of Protivity in dairy and beef calves of varying sources, including those raised in high population densities, high-stress situations and intensive calf-raising facilities. Only antimicrobials that had no activity against M. bovis were allowed. In this study, a total of 1,069 calves (355 unvaccinated controls and 714 vaccinated with Protivity) were enrolled at three distinct geographical locations. The age range of the calves enrolled were between 8 days of age and younger and approximately 30 days of age. The calves were administered Protivity (n = 714) by subcutaneous route on Day 0 and Day 21 of the experiment design. The frequency of adverse events (mainly neonatal diarrhea and respiratory infections, which are common in this age of calves) in the control and vaccinated groups were similar. One out of 714 (0.14%) vaccinated calves developed arthritis where the vaccine strain was isolated from the affected joint

Zoetis - 10023423 - Protivity [50 ds] Highlights:

• SKU: 28105
• Manufacturer: Zoetis
• Application: Injection
• For use with: Beef, Dairy
• Ailment: MYCOPLASMA BOVIS
• Use entire contents when first opened
• Inactivate unused contents before disposal
• Do not vaccinate within 21 days before slaughter
• Sterilized syringes and needles should be used to administer this vaccine
• Do not sterilize with chemicals because traces of disinfectant may inactivate the vaccine