Dexium [100 mL]

Dexamethasone Solution is a synthetic analogue of prednisolone, having similar but more potent anti-inflammatory therapeutic action and diversified hormonal and metabolic effects. Modification of the basic corticoid structure as achieved in Dexium offers enhanced anti-inflammatory effect compared to older corticosteroids. The dosage of Dexium required is markedly lower than that of prednisone and prednisolone. Dexium is not species-specific; however, the veterinarian should read the sections on INDICATIONS, DOSAGE, SIDE EFFECTS, CONTRAINDICATIONS, PRECAUTIONS, and WARNINGS before this drug is used. Dexium is intended for intravenous or intramuscular administration. Each mL contains 2 mg dexamethasone, 500 mg polyethylene glycol 400, 9 mg benzyl alcohol, 1.8 mg methylparaben and 0.2 mg propylparaben as preservatives, 4.75% alcohol, HCl to adjust pH to approximately 4.9, water for injection q.s.

INDICATIONS:
Dexium is indicated for the treatment of primary bovine ketosis and as an anti-inflammatory agent in the bovine and equine. As supportive therapy, Dexium may be used in the management of various rheumatic, allergic, dermatologic, and other diseases known to be responsive to anti-inflammatory corticosteroids. Dexium may be used intravenously as supportive therapy when an immediate hormonal response is required.

Bovine Ketosis
Dexium is offered for the treatment of primary ketosis. The gluconeogenic effects of Dexium, when administered intramuscularly, are generally noted within the first 6 to 12 hours. When Dexium is used intravenously, the effects may be noted sooner. Blood sugar levels rise to normal levels rapidly and generally rise to above normal levels within 12 to 24 hours. Acetone bodies are reduced to normal concentrations usually within 24 hours. The physical attitude of animals treated with Dexium brightens and appetite improves, usually within 12 hours. Milk production, which is suppressed as a compensatory reaction in this condition, begins to increase. In some instances, it may even surpass previous peaks. The recovery process usually takes from 3 to 7 days.

Supportive Therapy
Dexium may be used as supportive therapy in mastitis, metritis, traumatic gastritis, and pyelonephritis, while appropriate primary therapy is administered. In these cases, the corticosteroid combats accompanying stress and enhances the feeling of general well-being.

Dexium may also be used as supportive therapy in inflammatory conditions such as arthritic conditions, snake bite, acute mastitis, shipping fever, pneumonia, laminitis, and retained placenta.

Equine
Dexium is indicated for the treatment of acute musculoskeletal inflammations, such as bursitis, carpitis, osselets, tendonitis, myositis, and sprains. If boney changes exist in any of these conditions, joints or accessory structures, a response to Dexium cannot be expected. In addition, Dexium may be used as supportive therapy in fatigue, heat exhaustion, influenza, laminitis, and retained placenta provided that the primary cause is determined and corrected.

ADMINISTRATION AND DOSAGE:
Therapy with Dexium, as with any other potent corticosteroid, should be individualized according to the severity of the condition being treated, anticipated duration of steroid therapy, and animal's threshold or tolerance for steroid excess. Treatment may be changed over to Dexium from any other glucocorticoid with proper reduction or adjustment of doage.

Bovine:
Dexium: 5 - 20 mg intravenously or intramuscularly.

Equine:
Dexium: 2.5 - 5 mg intravenously or intramuscularly.

Dexium [100 mL] Highlights: 

• SKU: 28539
• Manufacturer: Bimeda
• Callicrate Loops are made from a specific latex formulation that is over three times stronger than surgical tubing or pre-made latex rings.
• The patented no-slip Callicrate Clip that holds the necessary loop tension, combined with the extra strength latex, gives immediate and total occlusion (blocking of the blood vessels), which means less pain and stress. It also eliminates swelling, resulting in faster scrotal drop time.
• Special lubrication reduces friction and abrasions and assures uniform stretching around the scrotum for complete ligation.
• Eliminate guesswork – the Callicrate Bander “custom fits” every loop to the correct size for each animal.
• Makes all other methods of castration obsolete and allows you to manage your bull calves for maximum profit!
• Allows you to take advantage of the increase weight gain of bulls while eliminating the stress and complications of elastrator rings and surgical